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[1] A common starting regimen in adults with normal renal and hepatic function is 1 mL intramuscularly once or twice weekly, titrated every four weeks according to biochemical markers such as fasting lipid panel, liver transaminases, and serum carnitine

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Samples were analyzed for a variety of metabolic variables (e.g., glucose, HbA1c, lipid panel, C-reactive protein, nitrate/nitrite, and several markers of oxidative stress)

Using metronidazole, it was estimated that approximately one quarter of daily methylmalonic acid production is derived from propionate synthesized in the large colon by anaerobic bacteria (160)