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Description
Sustained cysteine supply via SLC7A11 maintains high intracellular GSH levels, which are required to support the catalytic activity of downstream effectors, such as GPX4

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The injection involved inserting the needle from the lower pole to the upper pole of the kidney and gradually withdrawing it after administering the rAAV9 solution
EMT is typified by loss of epithelial traits (including cell polarity and cell-cell junctions) and acquisition of mesenchymal traits (including fibroblastic spindle-shaped morphology) to increase the mobility of tumor cells