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LAT1-mediated prodrug uptake: A way to breach the bloodbrain barrier

Advanced glycation end products and protein carbonyl levels in plasma reveal sex-specific differences in Parkinsons and Alzheimers disease

We considered whether the higher levels of glutathione in animals treated with SIH (Figure 1E and F) could reflect a hormetic response to sublethal oxidative stress, which has been described for SIH at low concentrations (10 M) combining with the cellular labile iron pool within hepatocellular carcinoma cells in culture (Caro et al., 2015)
Irwin RE, Cook D, Richardson LL, Manson JS, Gardner DR

Watermann and Dringen 2023
