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Importantly, metabolic homeostasis is tightly controlled by thiolated tRNAs whose levels reciprocally regulate nucleotide synthesis, amino acid metabolism and carbohydrate metabolism 29,43

Widespread neuronal vacuolation with single or multiple large vacuoles, unexplained as to pathogenesis, is occasionally seen in dogs and cattle with progressive neurologic dysfunction
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Betsuyaku T, Fuke S, Inomata T, et al

Lately, it has been stated that G6PDH activity and expression, along with NADPH and GSH levels, were decreased in the rat kidney cortex during streptozotocin-induced diabetes, suggesting a close association between these parameters [214]
