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By limiting the literature search to PubMed, we might have missed studies from parts of the world where vitamin B12 deficiency could be endemic due to economic, cultural, or dietary/religious reasons
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Randomized, double-blind, placebo-controlled study of zeaxanthin and visual function in patients with atrophic age-related macular degeneration: The Zeaxanthin and Visual Function Study (ZVF) FDA IND #78, 973

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