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This leads to a significant loss of fluids and electrolytes, leaving you feeling parched and weak

Most scientists claim that pSTAT3 induced by exogenous leptin treatment are reduced in the hypothalamus of DIO mice [139] evidenced mainly by the results from three different kind of investigations, and believe this decrease contributes to the mechanism of central leptin resistance [72, 140,141,142,143,144,145,146]

10.1038/nature02006 30 DobbsR.ChoeS.KalmanekE.HarringtonD