glutathione-disulfide reductase bacteria Frontiers Glutathione reductase modulates endogenous oxidative

In addition, ROS influence the flux of Ca 2+ ions, since many Ca 2+ handling proteins, including inositol 1,4,5 trisphosphate receptors (IP 3 Rs), SERCA pumps or regulators of the mitochondrial Ca 2+ uniporter (MCU) are redox-sensitive

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All procedures adhered to Chinese regulations on animal care and use and were approved by the Animal Ethics Committee of Fujian Medical University

While selectivity over classical ERs is reported at relevant concentrations, nuclear-receptor cross-reactivity and downstream network effects remain theoretical risks in longer or higher-exposure studies

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