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It was revealed that Vit C increases to induce midbrain-derived neural stem cells into dopaminergic neurons by increasing 5-hydroxymethylcytosine and decreasing histone H3 lysine 27 tri-methylation generation in the dopamine phenotype gene promoters, which are catalyzed by ten-eleven-translocation 1 (Tet1) methylcytosine dioxygenase 1 and histone H3K27 demethylase (Jmjd3), respectively
doi: 10.3109/10715762.2015.1022540
however, impairment of hepatocellular function occurs and gastric injury may develop (21)
[PubMed] [Google Scholar] 389
Gieryng A, Pszczolkowska D, Walentynowicz KA, Rajan WD, Kaminska B
