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For in-vitro laboratory handling only

Variations in CpG site methylation within the Htt gene have been observed in the mouse Htt gene knock-in model, the transgenic HTT sheep model, and humans (Lu et al., 2020)

This sub-analysis evaluated the efficacy and safety of once-weekly cagrilintide 2.4 mg monotherapy, plus lifestyle intervention, for adults with obesity or overweight and a weightrelated comorbidity without diabetes

Nine GSH measurements (three OA from the IFC baseline, two OA from the IPL baseline, three OA from the IFC task condition, and one YA for the IFC task) were excluded for a fitting error (defined as the standard deviation of the model residuals divided by the amplitude of the fitted GSH signal) above 3 SD

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