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Anche meta-analisi successive riportano riduzioni modeste ma significative del peso corporeo, dellIMC o della massa grassa, con effetti pi rilevanti nelle popolazioni in sovrappeso o obese
Elevated TMAO levels are linked to increased cardiovascular risk, including atherosclerosis and heart attacks
However, because of the premature study termination and the aggressive HbA1c goal, the neuropathy outcome in the ACCORD trial is difficult to interpret
