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Cleavage was carried out with 95% trifluoroacetyl (TFA), 2.5% water, and 2.5% triisopropylsilane for up to 3 h, followed by diethyl ether precipitation and preparative HPLC on C18 reverse phase columns using 0.1% TFA in water and 0.1% TFA in acetonitrile as eluents, followed by lyophilization
In addition to the above, isorhapontigenin mitigates diabetic cardiac microvascular injury by inhibiting mitochondria-associated ferroptosis via the PRDX2/MFN2/ACSL4 pathway [111]
