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Particularly, we found that mean plasma levels of Valine (U:140.9 mol/L, K:127.8 mol/L), Lysine (U:109.9 mol/L, K:95.7 mol/L), Threonine (U:67.5 mol/L, K:57.9 mol/L) and Tryptophan (U:2.9 mol/L, K:2.3 mol/L), fell below the expected ranges for healthy adolescents (UCSF Clinical Core Accepted Reference Ranges) for both those affected with konzo and their unaffected siblings

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Role of SUMO in the dynamics of telomere maintenance in fission yeast

We also found that high glucose in young explants increased expression of the glutamine pathway genes glutaminase (GLS), glutamate dehydrogenase 1 (GLUD1), solute carrier family 1 member 5 (SLC1A5), and glutamic-oxaloacetic transaminase (GOT1)