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doi: 10.1038/nrd781

MOTS-C activates AMPK pathways to improve insulin sensitivity, mitochondrial function, and metabolic flexibility

However, if youre not deficient in B12, additional supplementation may not provide significant benefits

If a deficiency is linked to a chronic condition like pernicious anemia, Crohns, or celiac disease, you might need injections for the long haul to bypass the digestive system entirely

Study Obes., vol
