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Diabetes Mellitus and Risk of Dementia: A Meta-Analysis of Prospective Observational Studies

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First, the intact nuclei and large debris pellet were discarded after centrifugation at 700 g for 1 min

436 Like IRE1, PERK is normally inhibited by BiP binding, and its activation consists of BiP dissociation, homodimerization, and trans-autophosphorylation, allowing the recruitment and phosphorylation of other target proteins
Nature 587 , 555566 (2020)
