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By using LAT1-4F2hc as the model, we found that the LAAM GSH-CQDs could bind to the LAT1 mainly through hydrogen bonds formed between the amino acid groups on LAAM GSH-CQDs and the Glu457, Glu78, Asn242 and Leu238 residues in LAT1 with a docking energy of 8.80 kcal mol 1 (Supplementary Fig
(PubMed) Song GG, Bae SC, Lee YH
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doi: 10.1159/000441293
Moreover, when the extract was administered followed by APAP as a therapeutic approach, it could even potentiate APAP-induced hepatotoxicity [106]
