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Targeting ferroptosis: The recognition that iron-mediated oxidative damage (ferroptosis) plays a role in POCD has led to exploring iron chelators

This has a strong influence on their reactivity, affecting such properties as their accessibility and protonation state (i.e., p K a )

Cascio S, Chandler C, Zhang L, Sinno S, Gao B, Onkar S, et al

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