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A B12 deficiency can cause demyelination, leading to neuropathy with neurological signs like numbness, pins and needles, and muscle weakness, especially in the feet and hands

G., Tapper, S., & Edden, R

In 1994, the Framingham Heart Study reported the prevalence of vitamin B 12 deficiency, as defined by a serum vitamin B 12 level less than 200 pg per mL and elevated levels of serum homocysteine, methylmalonic acid, or both, to be 12 percent among 548 community-dwelling older patients

J., Hovig, E