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The median lethal dose (LD 50 ) of hydrogen cyanide ranges from 2,500 to 5000 mg min m 3 , and the maximum acceptable cyanide concentration in drinking water is 0.5 mg L 1 for over 5 days (or 1.9 M), as per the WHO

Membrane transport proteins in human melanoma: associations with tumour aggressiveness and metastasis

1100 mg/mL) produced no significant effects on viability, apoptosis or oxidative stress in either cell line, even at highest concentrations [116]

The potential interference of NAC with the effectiveness of standard chemotherapy critically depends on whether the specific chemotherapy depends on ROS production