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Yan W, et al
After sports-related concussions, neuronal damage occurs alongside an increase in pro-inflammatory cytokine levels
PLGA is biocompatible and is gradually degraded by the body, allowing for prolonged drug release
This active targeting strategy not only reduces siRNA accumulation in unintended tissues, thus decreasing or avoiding undesired side effects and toxicity, but also achieves potent gene silencing at a low dosage
