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Special Considerations: Do not use in patients with G6PD deficiency or severe kidney disease Use caution in those with a history of nephrolithiasis or oxalate metabolism disorder

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But a monthly 4000 mcg dose would be 4 mL, with the same concentration

see Table 1) (EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2015)

High levels of homocysteine are associated with an increased risk of developing cardiovascular disease