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For example, AMPK-activating mimetics (such as AICAR or metformin) have been experimentally combined with mTOR inhibitors (e.g., rapamycin) to reduce kidney tumor size in a nude mouse model [324]
Although we do not know the exact mechanism, we hypothesize that Ab68 antibody will have the same effect-suppressing inflammation by reducing the infiltration of inflammatory cells in multiple organs
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Lockley SW, Skene DJ, Arendt J, Tabandeh H, Bird AC, Defrance R
Faskowitz AJ, Kramskiy VN, Pasternak GW
