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By 2000, the virus had spread to Costa Rica, where it was first detected in Litopenaeus vannamei farms in the Gulf of Nicoya [52]

Patients should record the severity and the frequency of seizures in a seizure diary

CarruthersBMvan de SandeMIDe MeirleirKLKlimasNGBroderickGMitchellTet al

developed a biomimetic nanomodulator targeting sepsis-associated encephalopathy, which crossed the blood-brain barrier, alleviated oxidative stress, polarized macrophages toward anti-inflammatory phenotypes, and improved cognition and survival (Qu et al., 2024)

The microfluidic device was intended for drug permeability test, and pharmacokinetics (PK) and pharmacodynamics (PD) evaluation whereby the test drug could be delivered either to the upper or bottom channel via a pressure-driven flow to mimic dynamic in vivo conditions, but it could also be adapted to microbiome studies (Kimura et al., 2015)