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Both peptides inhibited the enzymatic activity of Lm PC-PLC toward the synthetic substrate 4-NPPC, but NS-26 was significantly stronger than NE-6, with IC50 values of 9.4 M (95% CI 4.9 to 33.9 M) and 43.8 M (95% CI 36.1 to 54.7 M), respectively (Fig
The gut microbial endocrine organ: bacterially derived signals driving cardiometabolic diseases
