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For example, widely prescribed fluoroquinolone antibiotics are usually prescribed to treat various infections such as pneumonia and sinusitis (173175)

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Because folate supplementation can efficiently reduce plasma homocysteine levels, both in the fasting state and after methionine loading, results from further prospective cohort studies and from on-going interventional trials will determine whether homocysteine-lowering therapies can contribute to the prevention and reduction of cardiovascular risk

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That is important, because it confirms that VEGFR2 is not just one of many mechanisms, but truly a causal pathway