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Anti-anxiety effects in rats at 0.5 g/kg (extremely low dose) produced effects within 12 minutes of intraperitoneal injection, including increased time exploring open/lighted maze areas, decreased immobile freeze reaction time, and increased exploration in open field tests

In summary, this study reveals a novel mechanism by which gut bacteria promote uric acid homeostasis in the host, highlighting the potential significance of targeting the gut microbiota as a therapeutic approach for hyperuricemia

[35] During this period, Clooney was a student at the Beverly Hills Playhouse acting school for five years

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