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The duration of effects varies per individual, depending on metabolism, lifestyle, and initial deficiency levels
[DOI] [PubMed] [Google Scholar] Baric M, Sever AZ, Vuletic LB, et al

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Persistently low B12 levels can cause pernicious anemia, stomach problems or nerve damage

Depression increases the number of reactive oxygen species, causing mitoc stress in the body that lowers the antioxidants [116]