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Published April 4, 2012
Phenotypes of organ involvement in sarcoidosis
Tryptophan hydroxylase represents the rate-limiting step in serotonin and melatonin synthesis
Conversely, astrocytic activation can also lead to pro-inflammatory cytokine release, alongside increased concentrations of chemokines and reactive oxygen species and microglial activation (Sochocka et al., 2017) resulting in increased excitotoxicity, apoptosis and neurodegeneration
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