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The time point of 60 min to determine oral bioavailability of the interventional product was decided based on the published t max of approximately 45 min after oral ingestion of NAC (Borgstrom and Kagedal, 1990) and that of approximately 75 min of glycine in blood plasma of healthy volunteers (Butterworth et al., 1958)

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[DOI] [PubMed] [Google Scholar] [445].Lynch JL, Gallus NJ, Ericson ME, Beitz AJ, Analysis of nociception, sex and peripheral nerve innervation in the TMEV animal model of multiple sclerosis, Pain 136(3) (2008) 293304

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Missing doses does not cause harm but interrupts the lipotropic pathway support, which may delay measurable fat metabolism outcomes
