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Begara-Morales et al

Another drawback to these tests is that other factors, such as inflammation, can cause these biomarkers to be abnormally high

The increase in the endogenous production of ROS and reactive nitrogen species (RNS) in asthmatics, due to insult of both structural cells (epithelium, fibroblasts, smooth muscle cells, etc.) and cells of the immune system (macrophages, neutrophils, eosinophils, etc.), seems to be directly linked to severity of asthma [4,7,10], even in the case of apparently good clinical control [89]

DSIP, short for Delta Sleep-Inducing Peptide, is a naturally occurring peptide that was first identified in the 1970s

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