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however, it failed to reach statistical significance ( P =0.1)

Several studies have already investigated later stages of the disease

Upregulation of carbonyl reductase 1, an enzyme that protects cells against oxidative stress and cell death by inhibiting the formation of lipid peroxides, was observed in SFN-pretreated hepatic IRI mice in an Nrf2-dependent manner (Kwon et al., 2019)

doi: 10.1002/fft2.50 [DOI] [Google Scholar] [452].Brown K, Theofanous D, Britton RG, et al
