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There are several clinical assessment scales which have been developed for objective and reliable evaluation of CIPN, such as common toxicity criteria of the national cancer institute (NCI-CTC), and the total neuropathy score (TNS) (Cavaletti et al., 2013)

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Long-term safety and efficacy of preladenant in subjects with fluctuating Parkinson''s disease

NI are phosphorylated within cells by the activity of cellular kinases, bind as triphosphates to the active center of the HCV-specific NS5B polymerase, and abort the construction of the growing viral RNA chain