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found that intracellular copper accumulation could promote radiotherapy resistance in multiple cancers including hepatic carcinoma, nasopharyngeal carcinoma and colorectal cancer [187]
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Cloning and functional characterization of a new subtype of the amino acid transport system N
In contrast to the acute wounds described above, which typically show signs of healing in less than four weeks following the normal progression of wound healing, chronic wounds are generally characterized by elevated bacterial levels caused by hyperglycemia along with high inflammatory cytokine levels, increased protease and ROS levels, a degraded nonfunctional ECM, reduced mitogenic activity, and enhanced cell senescence [131, 132, 158]
