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Additionally, this study found that these changes correlate with disease activity and severity

Notably, 13 genes and their corresponding proteins were upregulated in group H-IMF, including LCN2 (Lipocalin 2), MPO (Myeloperoxidase), CATHL4 (Cathelicidin 4), ACAN (Aggrecan), TTN (Titin), CATHL3 (Cathelicidin 3), CHAD (Chondroadherin), PGLYRP1 (Peptidoglycan Recognition Protein 1), AZU1 (Azurocidin 1), COL2A1 (Collagen Type II Alpha 1 Chain), PRG3 (Proteoglycan 3), and NGP (Neutrophilic Granule Protein)