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These recent findings suggest that, while -cells express low levels of catalase and glutathione peroxidase, they possess an antioxidant defense that requires thioredoxin and thioredoxin reductase for regeneration through reduction of oxidized peroxiredoxins

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Golgi matrix protein 130 (GM130) [113]can up-regulate the inhibition of the autophagy-lysosome pathway, maintain appropriate autophagy to prevent the damage of tight connections, maintain BBB function, and reduce brain parenchymal injury

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doi: 10.1021/sb500252a [DOI] [PMC free article] [PubMed] [Google Scholar] 46

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Similarly, we also confirmed the comparable peptide mapping results between the alkaline washed and control samples (Supplementary Fig

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The treatment, which was previously indicated only for symptomatic children 3 years of age and older with late infantile CLN2 disease, also known as Batten disease, can now be given to diagnosed children of all ages, regardless of whether they are symptomatic or presymptomatic

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