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Common Mild Side Effects Short-term redness or slight irritation at the injection site Light water retention, especially during the initial weeks Increased appetite Mild headaches (rare and usually transient) Temporary fatigue or lightheadedness immediately after injection Who Should Avoid This Therapy People with an active cancer diagnosis or history of cancer, as GH secretagogues increase cellular replication rates Pregnant or breastfeeding individuals should avoid this therapy due to insufficient safety data on its effects during these stages

Clin Exp Pharmacol Physiol 42(6):632639

Nitric oxide is a highly toxic element that by itself blocks nerve conduction, especially in demyelinated axons, and stimulates apoptosis

10.3390/ph17060677 [DOI] [PMC free article] [PubMed] [Google Scholar] 12.Eker F, Duman H, Akdai E, Bolat E, Sarta S, Karav S, et al

Expression of the GRHPR gene is seen in most tissues with the highest levels in the liver and then the kidney