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Rescue by N-acetyl Cysteine

Despite limited effects on offspring mice, PCs continue to show potential as a treatment for GDM, but their long-term safety and mechanisms require further research and verification

The roles of various lncRNAs in autophagy-induced chemoresistance have previously been reviewed (6), including bladder cancer-associated transcript 1 (BLACAT1), metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), the X-inactivate specific transcript (XIST), small nucleolar RNA host genes ( SNHGs ), highly upregulated in liver cancer (HULC), and cancer susceptibility candidate 2 (CASC2)

For example, in NMDA-injected brain, healthy neurons are observed in the penumbra region near activated astrocytes whereas in kainic acid-injected brain, both astrocytes and neurons gradually die off [43]

Microglial surveillance and response mechanisms in the healthy and damaged brain In healthy brains, microglia continuously sense the alterations in CNS microenvironment by extending and retracting their processes