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By its antioxidant effect, VIC can inhibit the oxidation of proteins, lipids, carbohydrates, and nucleic acids and affects the regulation of immune function by acting as a cofactor for enzymes involved in gene synthesis and expression

Time to rename COPD exacerbations: implementing the term lung attack

Moreover, leptin promotes the activation of Kupffer cells, the livers resident macrophages, enhancing the release of inflammatory cytokines such as TNF-, IL-6, and IL-1

The reperfusion occurring after ischemia elicits pathogenic processes, exacerbating injury caused by ischemia per se [213]