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(2011) isolated phenolic compounds from the mushroom Phellinus linteus showed the anti-inflammatory mechanisms of decreasing the level of MDA in the edemapaw by enhancing the effect of SOD, GPx, and GRx in the liver, further the suppression of TNF- and NO

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Although SeChry did not affect the uptake of cysteine, it did increase glutathione depletion, indicating that it might induce oxidative stress, which will be scavenged by GPX4, a selenium-dependent enzyme

Kumar MA, Baba SK, Sadida HQ, Marzooqi SA, Jerobin J, Altemani FH, Bhat AA

Neuroinflammation as a neurotoxic mechanism in alcoholism: commentary on Increased MCP-1 and microglia in various regions of human alcoholic brain