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In this sense, 538 kinases have been identified that comprise the human kinome, and an example of them are glycolytic enzymes, i.e., hexokinase, phosphofructokinase, aldolase, phosphoglycerate kinase, and pyruvate kinase [21, 26]

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The applicant provided 10 studies to support these claims

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Conclusion and perspective Ferroptosis, characterized by iron-dependent lipid peroxidation, presents a unique avenue for targeting cancer cells with specific vulnerabilities

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The metabolic alterations induced by KRAS mutations also promote resistance to ICIs

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