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This may mediate activation of perivascular Ms, microglia, and astrocytes, and initiate further immune responses within the brain parenchyma, suggesting neuroinflammation can be triggered by signaling from the periphery, without primary injury or disease originating within the CNS

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Radtke et al., 2012)

The IL-1 level indicates the activation of the inflammatory cascade, while the levels of IL-6 and TNF- are known to mediate and amplify inflammatory processes

Works Within 30 Minutes, Not Hours IV medications reach therapeutic levels quickly: anti-inflammatory pain relief typically starts within 30 minutes, anti-nausea medicine calms vomiting within 1530 minutes, and magnesium begins stabilizing nerves within 1560 minutes