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150 : 4044 Lippoldt A, Padilla CA, Gerst H, Andbjer B, Richter E, Holmgren A and Fuxe K (1995) Localization of thioredoxin in the rat brain and functional implications

In this case, the B12 shots have started to heal the damaged neurons myelin sheath, but the neural network in which the healed neuron is in, is in a super sensitive state (with extra receptors), so the patient may feel pain or other unpleasant sensations

Whenever this type of diet is followed, it may be useful to opt for vitamin B12-enriched products, such as rice- and soy-base drinks

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Nuclei were pelleted at 400 g at 4C for 5 minutes and resuspended in isolation buffer consisting of 1 mg/mL BSA in nuclease free DPBS supplemented with RNase (0.4 U/L RNasin, Promega