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10.1182/blood.2021011597 44 FuruhashiM.HotamisligilG

Oxidative stress and mitochondrial damage have been implicated in the pathogenesis of several brain disorders including PD [41]

Why It Was in Category 2 Despite decades of clinical use in Russia (where it is an approved pharmaceutical), Semax was placed in Category 2 in the US due to safety concerns, likely related to the limited data from US-standard clinical trials and the regulatory gap between international evidence and FDA requirements

Functional characterization of des-IGF-1 action at excitatory synapses in the CA1 region of rat hippocampus