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Assessing exposure to atrazine and its metabolites using biomonitoring

High intakes of choline or carnitine can be converted by gut bacteria to trimethylamine, creating a transient fish-like smell in sweat or breath

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PT-141, lacking this protection, is more susceptible to trypsin-like cleavage at the Arg-Trp and Lys C-terminal bonds

FAO in the resistant cells was revealed to be a targetable vulnerability when FAO was inhibited by siRNAs against FA genes and etomoxir, resulting in increased sensitivity to ven/aza (Stevens et al., 2020)