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Tables 1 and 2 summarize passive membrane diffusion and active transport membrane permeability, respectively, for select small molecule NNMT inhibitors for which structure activity relationships had been previously developed.[17] 1-MNA, a product inhibitor of NNMT[12, 24, 25] exhibited no passive permeability (Table 1)

[DOI] [PMC free article] [PubMed] [Google Scholar] 51.Nigwekar S.U., Kang A., Zoungas S., et al

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