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Lastly, they propose that tirzepatide causes a thermogenic-like amino acid profile in BAT, which could explain why obese IR mice have lower systemic BCAA levels [82]

The researchers went on to theorize that the downregulation of the HER-2/neu gene found in mammary adenocarcinoma is responsible for epitalons ability to inhibit the spontaneous production of mammary tumors in HER-2/neu mice ( Effects of Epitalon on Female Mouse Anatomy Epitalon is considered a strong antioxidant that could potentially be beneficial for longevity purposes

It is also shown in animal models to bolster biochemical feedback mechanisms along the gut-brain axis [2, 4, 22]