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This data, along with the lack of formation of the thiolate-FAD charge transfer absorption when monitoring the C159S variant reductive half-reaction, confirms the residue responsible for this observed transition

These peripheral patterns support a testable hypothesis that toxic metal burden, redox-sensitive inflammatory signaling, and prostaglandin-pathway activation converge in biomarker-defined ASD subgroups

Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses and Gene Ontology (GO) enrichment analyses were conducted using R package clusterProfiler

(2026) Proceedings of the National Academy of Sciences of the United States of America

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