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Following chronic liver injury, HSCs proliferate, lose their vitamin A and undergo a major phenotypical transformation to -smooth muscle actin (-SMA) positive activated HSCs, which produce a wide variety of collagenous and non-collagenous extracellular matrix (ECM) proteins [168]

Terruzzi et al

, Abd El Azim, A
The combination keeps its chemical structure even when it is under stress that would break down other materials

Laser Treatment for Pigmentation Lasers like Q-switched Nd:YAG, Pico Laser, or Fractional CO2 target melanin pigment directly without damaging surrounding skin
