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In contrast, the ANG 1-7 peptide synthesized by ACE2 activity affect pro-oxidant pathways, preventing or attenuating cell damage induced by oxidative stress

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Wallert M, Ziegler M, Wang X, Maluenda A, Xu X, Yap ML, Witt R, Giles C, Kluge S, Hortmann M, Zhang J, Meikle P, Lorkowski S, Peter K (2019) -Tocopherol preserves cardiac function by reducing oxidative stress and inflammation in ischemia/reperfusion injury

Discussion Here we investigated the contribution of the TSS pathway to the antioxidant and ferroptosis stress regulation in SCD erythroblasts