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Description
PC and SM lipids are predominantly found in the outer leaflet of the membrane while the majority of PE and PI lipids, as well as, all PS and PG lipids are located on the inner leaflet (Mohandas and Gallagher, 2008)
PDE5 inhibitors enhance tumor permeability and efficacy of chemotherapy in a rat brain tumor model
Mol Pharm 15 , 36643671, (2018)
However, we will also highlight some of the challenges the field of PD therapeutics has been struggling with during the past decades
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