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No LD50 (lethal dose) has been established because researchers have not been able to achieve lethal toxicity in test animals
PubMed Central , StatPearls , StatPearls Publishing, 2026
If still undissolved, the powder may be degraded -- contact your pharmacy
[112] showed that the use of IN NPs delivery system enables the administration of a selective opioid receptor (DOR) agonist, leucine-kephalin hydrochloride (LENK), to the brain
